Proteomorphous objects from abiotic backbones

被引：67

作者：

Delsuc, Nicolas

Leger, Jean-Michel

Massip, Stephane

Huc, Ivan

机构：

[1] Inst Europeen Chim & Biol, F-33607 Pessac, France

[2] Lab Pharmacochim, F-33076 Bordeaux, France

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 1-2期

关键词：

chirality; helical structures; interactions; supramolecular chemistry; X-ray diffraction;

D O I：

10.1002/anie.200603390

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Big is beautiful: A folded synthetic molecule with a conformation that compares in size with the tertiary folds of a small protein and yet only consist of non-natural units is described. By not controlling the helical handedness allows the effect of tertiary interactions between helical modules through helix-helix side-by-side induction of handedness to be observed. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

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页码：214 / 217

页数：4

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