Connecting transcription to messenger RNA processing

被引：137

作者：

Proudfoot, N ^{[1
]}

机构：

[1] Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2000年 / 25卷 / 06期

关键词：

D O I：

10.1016/S0968-0004(00)01591-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The production of messenger RNA by gene transcription requires at least three RNA-processing mechanisms: capping, splicing and polyadenylation. All three reactions occur in intimate association with the elongating polymerase complex through the C terminus of the largest subunit of RNA polymerase II. The processing of mRNA is therefore orchestrated to act on the nascent RNA as soon as it emerges from the polymerase complex.

引用

页码：290 / 293

页数：4

共 41 条

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