In vivo gastroprotective effects of five Turkish folk remedies against ethanol-induced lesions

被引：54

作者：

Gürbüz, I

Üstün, O

Yesilada, E ^{[1
]}

Sezik, E

Akyürek, N

机构：

[1] Gazi Univ, Fac Pharm, Dept Pharmacognosy, TR-06330 Ankara, Turkey

[2] Gazi Univ, Fac Med, Dept Pathol, Ankara, Turkey

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2002年 / 83卷 / 03期

关键词：

anti-ulcerogenic activity; Asphodelus aestivus; Cichorium intybus; cytoprotective effect; Equisetum palustre; ethanol-induced gastric ulcer; histopathology; Laurus nobilis; Viscum album ssp album;

D O I：

10.1016/S0378-8741(02)00248-9

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Through evaluation of the data accumulated in Data Bank of Turkish Folk Remedies (TUHIB), five plant remedies, which are used to treat stomach ache were selected to test for their anti-ulcerogenic potency. In order to confirm the claimed activities, either decoction or methanol extracts were prepared from the roots of Asphodelus aestivus and Cichorium intybus, herbs of Equisetum palustre and Viscum album ssp. album and fruits of Laurus nobilis, according to their folkloric application way and tested for their effects on ethanol-induced gastric ulcer model in rats. Pharmacological experiments clearly demonstrated that the relevant extracts of all the plants given orally showed significant stomach protection against this model of ulcerogenesis. Results were further evaluated by using histopathological techniques. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：241 / 244

页数：4

共 7 条

[1] Evaluation of the gastroprotective effect of Laurus nobilis seeds on ethanol induced gastric ulcer in rats [J].