Evaluation of the gastroprotective effect of Laurus nobilis seeds on ethanol induced gastric ulcer in rats

被引:47
作者
Afifi, FU
Khalil, E
Tamimi, SO
Disi, A
机构
[1] UNIV JORDAN,FAC MED,AMMAN,JORDAN
[2] UNIV JORDAN,FAC SCI,AMMAN,JORDAN
关键词
Laurus nobilis; gastroprotective effect; acute toxicity; ethanol induced ulcer;
D O I
10.1016/S0378-8741(97)00070-6
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The possible antiulcerogenic activity of Laurus nobilis seeds was tested on experimentally (ethanol) induced gastric ulcer in rats. The results indicated antiulcerogenic activity for 20 and 40% aqueous extracts as well as for the oily fraction of these seeds. In acute toxicity studies, the aqueous extract was found safe with LD50 compared to oil LD50 0.33 ml/kg body weight. (C) 1997 Elsevier Science Ireland Ltd.
引用
收藏
页码:9 / 14
页数:6
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