Efficient planar chiral 2′-substituted 1,1′-P,N-ferrocene ligands for the asymmetric Heck reaction:: control of enantioselectivity and configuration by planar chiral substituent

被引：71

作者：

Deng, WP ^{[1
]}

Hou, XL ^{[1
]}

Dai, LX ^{[1
]}

Dong, XW ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Organomet Chem Lab, Shanghai 200032, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2000年 / 16期

关键词：

D O I：

10.1039/b003530k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Planar chiral 1,1'P,N-2'-substituted 2' substituted 1,1'-P,N-ferrocene derivatives were efficient ligands for the Pd-catalyzed asymmetric Heck reaction, in which 79-85% yields with high enantioselectivity (80-92%) were obtained within several hours; the enantioselectivity and the absolute configuration were controllable by changing the size of the planar chiral group and/or configuration of planar chirality.

引用

页码：1483 / 1484

页数：2

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