Regio- and stereocontrolled metal-mediated carbonyl propargylation or allenylation of enantiomerically pure azetidine-2,3-diones:: Synthesis of highly functionalized 3-substituted 3-hydroxy-β-lactams

被引：49

作者：

Alcaide, B ^{[1
]}

Almendros, P ^{[1
]}

Aragoncillo, C ^{[1
]}

机构：

[1] Univ Complutense, Fac Ciencias Quim, Dept Quim Organ 1, E-28040 Madrid, Spain

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 10期

关键词：

D O I：

10.1021/ol005736f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Regio and stereocontrolled metal-mediated Barbier-type reactions of azetidine-2,3-diones with differently substituted propargyl bromides offer an efficient asymmetric entry to densely functionalized 3-propargyl- (or allenyl-) substituted 3-hydroxy-beta-lactams.

引用

页码：1411 / 1414

页数：4

共 41 条

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