Axillary pH and influence of deodorants

被引:14
作者
Stenzaly-Achtert, S
Schölermann, A
Schreiber, J
Diec, KH
Rippke, F
Bielfeldt, S
机构
[1] BioSkin Inst Dermatol Forsch & Entwickling GmbH, D-22399 Hamburg, Germany
[2] Beiersdorf AG, Hamburg, Germany
关键词
experimental; trial; volunteers; efficacy; armpit; pH meter; malodor; deodorant;
D O I
10.1034/j.1600-0846.2000.006002087.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background/aims: In moist intertriginous regions, such as the armpit, the pH value is physiologically higher than in other skin regions. The regulation of the axillary pH-value was examined in an open study with 48 subjects in three groups with n=16 each. Methods: In the first 10 days (run-in) the subjects received a standard treatment in the axilla with shaving, cleansing and application of a pH-neutral deodorant. This was followed by a 5 day treatment period with the three test products (pH5 Eucerin(R) Deodorant Roll-on, Deodorant Balsam Spray, Deodorant cream). The study was concluded by a wash-out period with procedures identical to the run-in phase. The pH was measured with a calibrated pH-meter. Results: A significant pH reduction was shown during the treatment period when compared to the run-in phase. The Deodorant Roll-on induced a reduction of the mean pH values from 6.1 to 5.3, the Deodorant Balsam Spray from 6.5 to 5.7 and the Deodorant Cream from 6.2 to 5.3. During the wash-out period all pH values returned to baseline. Conclusion: All of the deodorants tested demonstrated a significant reduction in axillary pH. There is evidence that a high skin pH promotes the growth of several microorganisms that produce malodor. Therefore, the regulation of pH may contribute to the deodorant efficacy of the test products.
引用
收藏
页码:87 / 91
页数:5
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