Fusion pore in live cells

被引：16

作者：

Jena, BP ^{[1
]}

机构：

[1] Wayne State Univ, Dept Physiol, Sch Med, Detroit, MI 48201 USA

[2] Wayne State Univ, Dept Pharmacol, Sch Med, Detroit, MI 48201 USA

来源：

NEWS IN PHYSIOLOGICAL SCIENCES | 2002年 / 17卷

关键词：

D O I：

10.1152/nips.01394.2002

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Earlier electrophysiological measurements on live secretory cells suggested the presence of fusion pores at the plasma membrane, where secretory vesicles fuse to release vesicular contents. Recent studies using atomic force microscopy demonstrate for the first time the presence of the fusion pore and reveal its morphology and dynamics at near-nanometer resolution and in real time.

引用

页码：219 / 222

页数：4

共 20 条

[1] MICROFABRICATION OF CANTILEVER STYLI FOR THE ATOMIC FORCE MICROSCOPE [J].

ALBRECHT, TR ;

AKAMINE, S ;

CARVER, TE ;

QUATE, CF .

JOURNAL OF VACUUM SCIENCE & TECHNOLOGY A-VACUUM SURFACES AND FILMS, 1990, 8 (04) :3386-3396

[2] AN ATOMIC-RESOLUTION ATOMIC-FORCE MICROSCOPE IMPLEMENTED USING AN OPTICAL-LEVER [J].

ALEXANDER, S ;

HELLEMANS, L ;

MARTI, O ;

SCHNEIR, J ;

ELINGS, V ;

HANSMA, PK ;

LONGMIRE, M ;

GURLEY, J .

JOURNAL OF APPLIED PHYSICS, 1989, 65 (01) :164-167

[3] SPECTRIN-BASED MEMBRANE SKELETON - A MULTIPOTENTIAL ADAPTER BETWEEN PLASMA-MEMBRANE AND CYTOPLASM [J].

BENNETT, V .

PHYSIOLOGICAL REVIEWS, 1990, 70 (04) :1029-1065

[4] ATOMIC FORCE MICROSCOPE [J].

BINNIG, G ;

QUATE, CF ;

GERBER, C .

PHYSICAL REVIEW LETTERS, 1986, 56 (09) :930-933

[5] SINGLE-TUBE 3-DIMENSIONAL SCANNER FOR SCANNING TUNNELING MICROSCOPY [J].

BINNIG, G ;

SMITH, DPE .

REVIEW OF SCIENTIFIC INSTRUMENTS, 1986, 57 (08) :1688-1689

[6] The number of secretory vesicles remains unchanged following exocytosis [J].

Cho, SJ ;

Cho, J ;

Jena, BP .

CELL BIOLOGY INTERNATIONAL, 2002, 26 (01) :29-33

[7] Structure and dynamics of the fusion pores in live GH-secreting cells revealed using atomic force microscopy [J].

Cho, SJ ;

Jeftinija, K ;

Glavaski, A ;

Jeftinija, S ;

Jena, BP ;

Anderson, LL .

ENDOCRINOLOGY, 2002, 143 (03) :1144-1148

[8] Structure and dynamics of the fusion pore in live cells [J].

Cho, SJ ;

Quinn, AS ;

Stromer, MH ;

Dash, S ;

Cho, J ;

Taatjes, DJ ;

Jena, BP .

CELL BIOLOGY INTERNATIONAL, 2002, 26 (01) :35-42

[9]

CHO SJ, IN PRESS ANN NY ACAD

[10] Vimentin filaments in fibroblasts are a reservoir for SNAP23, a component of the membrane fusion machinery [J].

Faigle, W ;

Colucci-Guyon, E ;

Louvard, D ;

Amigorena, S ;

Galli, T .

MOLECULAR BIOLOGY OF THE CELL, 2000, 11 (10) :3485-3494

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