Fast and Selective Extraction of Sulfonamides from Honey Based on Magnetic Molecularly Imprinted Polymer

被引：115

作者：

Chen, Ligang ^{[1
]}

Zhang, Xiapan ^{[1
]}

Sun, Lei ^{[1
]}

Xu, Yang ^{[1
]}

Zeng, Qinglei ^{[1
]}

Wang, Hui ^{[1
]}

Xu, Haoyan ^{[1
]}

Yu, Aimin ^{[1
]}

Zhang, Hanqi ^{[1
]}

Ding, Lan ^{[1
]}

机构：

[1] Jilin Univ, Coll Chem, Changchun 130012, Peoples R China

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2009年 / 57卷 / 21期

关键词：

Magnetic molecularly imprinted polymer; sulfonamides; honey; liquid chromatography-tandem mass spectrometry; SOLID-PHASE EXTRACTION; PERFORMANCE LIQUID-CHROMATOGRAPHY; TANDEM MASS-SPECTROMETRY; ANTIBIOTIC-RESIDUES; CHLORAMPHENICOL; RECOGNITION; SAMPLES; BEADS; WATER;

D O I：

10.1021/jf902257d

中图分类号：

S [农业科学];

学科分类号：

082806 [农业信息与电气工程];

摘要：

A fast and selective method was developed for the determination of sulfonamides (SAs) in honey based on magnetic molecularly imprinted polymer. The extraction was carried out by blending and stirring the sample, extraction solvent and polymers. When the extraction was complete, the polymers, along with the captured analytes, were easily separated from the sample matrix by an adscititious magnet. The analytes eluted from the polymers were determined by liquid chromatography-tandem mass spectrometry. Under the optimal conditions, the detection limits of SAs are in the range of 1.5-4.3 ng g(-1). The relative standard deviations of intra- and interday ranging from 3.7% to 7.9% and from 4.3% to 9.9% are obtained, respectively. The proposed method was successfully applied to determine SAs including sulfadiazine, sulfamerazine, sulfamethoxydiazine, sulfamonomethoxine, suffadimethoxine, sulfamethoxazole and sulfaquinoxaline in different honey samples. The recoveries of SAs in these samples from 67.1% to 93.6% were obtained.

引用

页码：10073 / 10080

页数：8

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