Convergent synthesis of the BCDE-ring part of ciguatoxin

被引：32

作者：

Fujiwara, K ^{[1
]}

Koyama, Y ^{[1
]}

Kawai, K ^{[1
]}

Tanaka, H ^{[1
]}

Murai, A ^{[1
]}

机构：

[1] Hokkaido Univ, Grad Sch Sci, Div Chem, Sapporo, Hokkaido 0600810, Japan

来源：

SYNLETT | 2002年 / 11期

关键词：

heterocycles; stereoselective synthesis; natural products; polyethers; polycycles;

D O I：

10.1055/s-2002-34904

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The BCDE-ring part of ciguatoxin has been convergently synthesized by a sequence of reactions involving coupling of the E-ring part having a Z-enal group with the B-ring part as an acyl anion equivalent, selective removal of a p-bromobenzyl protective group using Miyaura's conditions, and reductive cyclization.

引用

页码：1835 / 1838

页数：4