Novel aziridine esters by the addition of aromatic nitrogen heterocycles to a 2H-azirine-3-carboxylic ester

被引：15

作者：

Alves, MJ ^{[1
]}

Ferreira, PMT

Maia, HLS

Monteiro, LS

Gilchrist, TL

机构：

[1] Univ Minho, Dept Chem, P-4710 Braga, Portugal

[2] Univ Liverpool, Dept Chem, Liverpool L69 7ZD, Merseyside, England

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 25期

关键词：

2H-azirines; aziridines; 5H-pyrrolo[1,2-c]imidazoles;

D O I：

10.1016/S0040-4039(00)00755-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Methyl 2-(2,6-dichlorophenyl)-2H-azirine-3-carboxoylate acts as an efficient alkylating agent for a variety of five-membered aromatic heterocycles. The aziridines derived from heterocycles that bear an alpha-carbonyl substituent react with TFA to give pyrroloimidazoles; 2,6-dichlorobenzaldehyde is also produced. (C) 2000 Elsevier Science Ltd. All rights reserved.

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收藏

页码：4991 / 4995

页数：5

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