Influence of motor symptoms upon the quality of life of patients with Parkinson's disease

被引：84

作者：

Gomez-Esteban, J. C.

Zarranz, J. J.

Lezcano, E.

Tijero, B.

Luna, A.

Velasco, F.

Rouco, I.

Garamendi, I.

机构：

[1] Hosp Cruces, Serv Neurol, Movement Disorders Unit, ES-48903 Baracaldo, Spain

[2] Univ Basque Country, Dept Neurosci, Bilbao, Spain

来源：

EUROPEAN NEUROLOGY | 2007年 / 57卷 / 03期

关键词：

D O I：

10.1159/000098468

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We studied the impact of various motor and nonmotor symptoms upon quality of life in patients with Parkinson's disease (PD). The study comprised 110 patients with PD (age: 68.6 years, course of the disease: 7.6 years). The Unified Parkinson Disease Rating Scale (UPDRS; I-IV) and Parkinson's Disease Questionnaire (PDQ-39) were recorded. We recorded the correlations between years of disease and UPDRS IV, as well as PDQ-39 and UPDRS I, II, III and IV. Introduction of all variables into a linear regression model showed that 3 variables accounted for 51% of the variance in PDQ-39. Mental condition, gait disorders and complications of dopaminergic drugs are the variables that most affect the quality of life of patients with PD. Copyright (c) 2007 S. Karger AG, Basel.

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页码：161 / 165

页数：5

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