Influence of motor symptoms upon the quality of life of patients with Parkinson's disease

被引：84

作者：

Gomez-Esteban, J. C.

Zarranz, J. J.

Lezcano, E.

Tijero, B.

Luna, A.

Velasco, F.

Rouco, I.

Garamendi, I.

机构：

[1] Hosp Cruces, Serv Neurol, Movement Disorders Unit, ES-48903 Baracaldo, Spain

[2] Univ Basque Country, Dept Neurosci, Bilbao, Spain

来源：

EUROPEAN NEUROLOGY | 2007年 / 57卷 / 03期

关键词：

D O I：

10.1159/000098468

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We studied the impact of various motor and nonmotor symptoms upon quality of life in patients with Parkinson's disease (PD). The study comprised 110 patients with PD (age: 68.6 years, course of the disease: 7.6 years). The Unified Parkinson Disease Rating Scale (UPDRS; I-IV) and Parkinson's Disease Questionnaire (PDQ-39) were recorded. We recorded the correlations between years of disease and UPDRS IV, as well as PDQ-39 and UPDRS I, II, III and IV. Introduction of all variables into a linear regression model showed that 3 variables accounted for 51% of the variance in PDQ-39. Mental condition, gait disorders and complications of dopaminergic drugs are the variables that most affect the quality of life of patients with PD. Copyright (c) 2007 S. Karger AG, Basel.

引用

页码：161 / 165

页数：5