Interpregnancy interval;
Preterm delivery;
Small for gestational age;
Early neonatal death;
Major congenital malformations;
FOLIC-ACID;
SUBSEQUENT RISK;
PRETERM BIRTH;
PREGNANCY;
STILLBIRTH;
DEFECTS;
MALNUTRITION;
ASSOCIATION;
MORTALITY;
WEIGHT;
D O I:
10.1016/j.contraception.2009.06.006
中图分类号:
R71 [妇产科学];
学科分类号:
100211 ;
摘要:
Background: The interpregnancy interval (IPI) has been reported to influence the outcome of pregnancy and birth. We performed a national study in Israel to determine the impact of IPI on multiple adverse perinatal outcomes. Study Design: This longitudinal cohort study used birth certificates of siblings born to the same biological mother, with at least one previous birth and a subsequent singleton pregnancy. Adverse pregnancy outcomes included preterm delivery, very preterm birth, small for gestational age (SGA), very SGA (VSGA), early neonatal death and major congenital malformations. Multivariate logistic regression was performed for each outcome. Results: The study included 440,838 of a total of 846,845 reported live births in Israel over 5 years; excluded were primiparas (32%), multifetal births (4.9%) and those with incomplete data (10.9%). For IPIs shorter than 6 months, there were significantly increased risks for preterm birth (OR=1.23), SGA (OR=1.14), VSGA (OR=1.15), early neonatal death (OR=1.62) and congenital malformations (OR=1.14). Intervals of 60 months or longer had higher risks for preterm birth (OR=1.39) and VSGA (OR=1.16). Conclusion: Optimal IPI recommendation of >11 months is an accessible and low-cost means to improve multiple adverse perinatal outcomes. (C) 2009 Published by Elsevier Inc.
引用
收藏
页码:512 / 518
页数:7
相关论文
共 29 条
[11]
Feinleib Manning, 2001, American Journal of Epidemiology, V154, pS60, DOI 10.1093/aje/154.12.S60
机构:
Washington Univ, Sch Med, Dept Pediat, Div Emergency Med, St Louis, MO 63110 USAWashington Univ, Sch Med, Dept Pediat, Div Emergency Med, St Louis, MO 63110 USA
McManemy, Julie
;
Cooke, Erinn
论文数: 0引用数: 0
h-index: 0
机构:Washington Univ, Sch Med, Dept Pediat, Div Emergency Med, St Louis, MO 63110 USA
Cooke, Erinn
;
Amon, Erol
论文数: 0引用数: 0
h-index: 0
机构:Washington Univ, Sch Med, Dept Pediat, Div Emergency Med, St Louis, MO 63110 USA
Amon, Erol
;
Leet, Terry
论文数: 0引用数: 0
h-index: 0
机构:Washington Univ, Sch Med, Dept Pediat, Div Emergency Med, St Louis, MO 63110 USA
机构:
Washington Univ, Sch Med, Dept Pediat, Div Emergency Med, St Louis, MO 63110 USAWashington Univ, Sch Med, Dept Pediat, Div Emergency Med, St Louis, MO 63110 USA
McManemy, Julie
;
Cooke, Erinn
论文数: 0引用数: 0
h-index: 0
机构:Washington Univ, Sch Med, Dept Pediat, Div Emergency Med, St Louis, MO 63110 USA
Cooke, Erinn
;
Amon, Erol
论文数: 0引用数: 0
h-index: 0
机构:Washington Univ, Sch Med, Dept Pediat, Div Emergency Med, St Louis, MO 63110 USA
Amon, Erol
;
Leet, Terry
论文数: 0引用数: 0
h-index: 0
机构:Washington Univ, Sch Med, Dept Pediat, Div Emergency Med, St Louis, MO 63110 USA