A facile and efficient nucleophilic displacement reaction at room temperature in ionic liquids

被引：45

作者：

Judeh, ZMA ^{[1
]}

Shen, HY ^{[1
]}

Chi, BC ^{[1
]}

Feng, LC ^{[1
]}

Selvasothi, S ^{[1
]}

机构：

[1] Natl Univ Singapore, Chem & Proc Engn Ctr, Singapore 117576, Singapore

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 51期

关键词：

nucleophilic displacement; ionic liquids; sodium salicylate; benzyl salicylate;

D O I：

10.1016/S0040-4039(02)02327-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We have investigated the use of room temperature ionic liquids as catalytic and environmentally benign solvents for the facile homogenous synthesis of benzyl salicylate by the nucleophilic displacement reaction between sodium salicylate and benzyl chloride. The reaction was found to proceed under relatively mild conditions with excellent conversion (up to 96%) without the use of PTCs. The ionic liquids were recycled and reused. The effect of temperature was also investigated. No by-products were observed after H-1 NMR and GC analysis. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：9381 / 9384

页数：4

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