Left ventricular diastolic dysfunction in patients with so-called lone atrial fibrillation

被引：93

作者：

Jaïs, P ^{[1
]}

Peng, JT ^{[1
]}

Shah, DC ^{[1
]}

Garrigue, S ^{[1
]}

Hocini, M ^{[1
]}

Yamane, T ^{[1
]}

Haïssaguerre, M ^{[1
]}

Barold, SS ^{[1
]}

Roudaut, R ^{[1
]}

Clémenty, J ^{[1
]}

机构：

[1] Hop Cardiol Haut Leveque, F-33604 Pessac, France

来源：

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY | 2000年 / 11卷 / 06期

关键词：

lone atrial fibrillation; hemodynamics; left ventricular diastolic function;

D O I：

10.1111/j.1540-8167.2000.tb00023.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Lone atrial fibrillation (AF) is defined by the absence of identifiable causes of AF, but its hemodynamics have not been investigated. Twenty-eight patients with lone AF were compared,vith 14 control patients referred for Wolff-Parkinson-White ablation, Transthoracic and transesophageal echocardiography were performed to rule out structural heart disease, followed by transseptally performed complete hemodynamic evaluation of the left heart systolic and diastolic function. There was no evidence of diastolic dysfunction according to echocardiographic criteria in AF and control patients. There was no difference in echocardiographic measurements, except for a significantly higher inferosuperior left atrial dimension seen in the four-chamber apical view in AF patients (51 +/- 10 vs 40 +/- 6 mm, P = 0.03). Hemodynamic evaluation showed that end-diastolic left ventricular pressure and the nadir of the left atrial Y descent were significantly higher in lone AF patients versus controls: 13 +/- 5 versus 8 +/- 3 mmHg (P = 0.001) and 6.7 +/- 3 versus 4.6 +/- 2.7 mmHg (P = 0.05). Our results demonstrated the presence of diastolic left heart dysfunction in patients with so-called lone AF.

引用

页码：623 / 625

页数：3

共 16 条

[11] Effects of atrial dilatation on refractory period and vulnerability to atrial fibrillation in the isolated Langendorff-perfused rabbit heart [J].