An efficient total synthesis of K-13, a non-competitive inhibitor of ACE I

被引：18

作者：

Bigot, A ^{[1
]}

Bois-Choussy, M ^{[1
]}

Zhu, JP ^{[1
]}

机构：

[1] CNRS, Inst Chim Subst Nat, F-91198 Gif Sur Yvette, France

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 23期

关键词：

D O I：

10.1016/S0040-4039(00)00695-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthesis of K-13, a non-competitive inhibitor of ACE I, with an endo biaryl ether bond is described. The key cycloetherification reaction of linear tripeptide 10 gave 17-membered macrocycle in quantitative yield. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：4573 / 4577

页数：5

共 37 条

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