Decorating multi-walled carbon nanotubes with quantum dots for construction of multi-color fluorescent nanoprobes

被引：28

作者：

Jia, Nengqin ^{[1
]}

Lian, Qiong ^{[1
]}

Tian, Zhong ^{[1
]}

Duan, Xin ^{[2
]}

Yin, Min ^{[1
]}

Jing, Lihong ^{[2
]}

Chen, Shouhui ^{[1
]}

Shen, Hebai ^{[1
]}

Gao, Mingyuan ^{[2
]}

机构：

[1] Shanghai Normal Univ, Dept Chem, Life & Environm Sci Coll, Shanghai 200234, Peoples R China

[2] Chinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China

来源：

NANOTECHNOLOGY | 2010年 / 21卷 / 04期

关键词：

INTRACELLULAR DELIVERY; CDTE NANOCRYSTALS; SINGLE-WALL; DNA; FUNCTIONALIZATION; CELLS; SIRNA;

D O I：

10.1088/0957-4484/21/4/045606

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Novel multi-color fluorescent nanoprobes were prepared by electrostatically assembling differently sized CdTe quantum dots on polyethylenimine (PEI) functionalized multi-walled carbon nanotubes (MWNTs). The structural and optical properties of the nano-assemblies (MWNTs-PEI-CdTe) were characterized by transmission electron microscopy (TEM), electron diffraction spectra (EDS), Raman spectroscopy, confocal microscopy and photoluminescence spectroscopy (PL), respectively. Electrochemical impedance spectroscopy (EIS) was also applied to investigate the electrostatic assembling among oxidized MWNTs, PEI and CdTe. Furthermore, confocal fluorescence microscopy was used to monitor the nano-assemblies' delivery into tumor cells. It was found that the nano-assemblies exhibit efficient intracellular transporting and strong intracellular tracking. These properties would make this luminescent nano-assembly an excellent building block for the construction of intracellular nanoprobes, which could hold great promise for biomedical applications.

引用

页数：8

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