Bioinspired chemical inversion of L-amino acids to D-amino acids

被引：77

作者：

Park, Hyunjung

Kim, Kwan Mook ^{[1
]}

Lee, Areum

Ham, Sihyun

Nam, Wonwoo

Chin, Jik

机构：

[1] Ewha Womans Univ, Dept Chem, Div Nanosci, Seoul 120750, South Korea

[2] Sookmyung Womens Univ, Dept Chem, Seoul 120742, South Korea

[3] Univ Toronto, Dept Chem, Toronto, ON M5S 1A1, Canada

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 06期

关键词：

D O I：

10.1021/ja067724g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An organic receptor (1) that binds a wide variety of amino acids with the same sense of stereoselectivity (D/L ratio of about 10) has been developed. This receptor binds amino acids by formation of imines with internal resonance-assisted hydrogen bonds much as in imines formed between pyridoxal and amino acids. The internal resonance-assisted hydrogen bond is used to activate the bound amino acids and convert L-amino acids to D-amino acids.

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页码：1518 / +

页数：3

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