Three dimensional outer volume suppression for short echo time in vivo H-1 spectroscopic imaging in rat brain

被引:10
作者
Chen, YJ [1 ]
Rachamadugu, S [1 ]
Fernandez, EJ [1 ]
机构
[1] UNIV VIRGINIA,DEPT CHEM ENGN,CHARLOTTESVILLE,VA 22903
关键词
three-dimensional spectroscopic imaging; lipid suppression; in vivo localization; short echo time; LOCALIZED H-1-NMR SPECTROSCOPY; NMR-SPECTROSCOPY; INVIVO; PRESATURATION;
D O I
10.1016/S0730-725X(97)00044-1
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Three-dimensional in vivo spectroscopic imaging in rat brain requires additional localization to reduce the effects of lipid contamination, Outer volume suppression has been shown to be effective in two dimensions. We have extended this approach to three dimensions with additional outer volume suppression conforming to the shape of the rat brain, The technique suppresses the pericranial lipid effectively, allowing sampling of volumes close to the skull and effective localized shimming, These benefits permit three-dimensional H-1 magnetic resonance spectroscopic imaging to be performed over most of the brain at shorter echo times, providing spectra more amenable to quantitative analysis. (C) 1997 Elsevier Science Inc.
引用
收藏
页码:839 / 845
页数:7
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