Agrobacterium tumefaciens soxR is involved in superoxide stress protection and also directly regulates superoxide-inducible expression of itself and a target gene

被引：21

作者：

Eiamphungporn, Warawan

Charoenlap, Nisanart

Vattanaviboon, Paiboon ^{[1
]}

Mongkolsuk, Skorn

机构：

[1] Chulabhorn Res Inst, Biotechnol Lab, Bangkok 10210, Thailand

[2] Mahidol Univ, Fac Sci, Dept Biotechnol, Bangkok 10400, Thailand

来源：

JOURNAL OF BACTERIOLOGY | 2006年 / 188卷 / 24期

关键词：

D O I：

10.1128/JB.00856-06

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Inactivation of Agrobacterium tumefaciens soxR increases sensitivity to superoxide generators. soxR expression is highly induced by superoxide stress and is autoregulated. SoxR also directly regulates the superoxide-inducible expression of atu5152. Taken together, the physiological role of soxR and the mechanism by which it regulates expression of target genes make the A. tumefaciens SoxR system different from other bacterial systems.

引用

收藏

页码：8669 / 8673

页数：5

相关论文

共 28 条

[1] MOLECULAR CHARACTERIZATION OF THE SOXRS GENES OF ESCHERICHIA-COLI - 2 GENES CONTROL A SUPEROXIDE STRESS REGULON [J].

AMABILECUEVAS, CF ;

DEMPLE, B .

NUCLEIC ACIDS RESEARCH, 1991, 19 (16) :4479-4484

[2] ohrR and ohr are the primary sensor/regulator and protective genes against organic hydroperoxide stress in Agrobacterium tumefaciens [J].

Chuchue, T ;

Tanboon, W ;

Prapagdee, B ;

Dubbs, JM ;

Vattanaviboon, P ;

Mongkolsuk, S .

JOURNAL OF BACTERIOLOGY, 2006, 188 (03) :842-851

[3]

CLAROS MG, 1994, COMPUT APPL BIOSCI, V10, P685

[4] Redox signaling and gene control in the Escherichia coli soxRS oxidative stress regulon - A review [J].

Demple, B .

GENE, 1996, 179 (01) :53-57

[5]

Demple B, 1999, BIOCHEM SOC SYMP, P119

[6] The phenazine pyocyanin is a terminal signalling factor in the quorum sensing network of Pseudomonas aeruginosa [J].

Dietrich, Lars E. P. ;

Price-Whelan, Alexa ;

Petersen, Ashley ;

Whiteley, Marvin ;

Newman, Dianne K. .

MOLECULAR MICROBIOLOGY, 2006, 61 (05) :1308-1321

[7] Direct nitric oxide signal transduction via nitrosylation of iron-sulfur centers in the SoxR transcription activator [J].

Ding, HG ;

Demple, B .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (10) :5146-5150

[8] Oxidant-inducible resistance to hydrogen peroxide killing in Agrobacterium tumefaciens requires the global peroxide sensor-regulator OxyR and KatA [J].

Eiamphungporn, W ;

Nakjarung, K ;

Prapagdee, B ;

Vattanaviboon, P ;

Mongkolsuk, S .

FEMS MICROBIOLOGY LETTERS, 2003, 225 (01) :167-172

[9] OXIDATIVE STRESS RESPONSES IN ESCHERICHIA-COLI AND SALMONELLA-TYPHIMURIUM [J].

FARR, SB ;

KOGOMA, T .

MICROBIOLOGICAL REVIEWS, 1991, 55 (04) :561-585

[10] Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58 [J].

Goodner, B ;

Hinkle, G ;

Gattung, S ;

Miller, N ;

Blanchard, M ;

Qurollo, B ;

Goldman, BS ;

Cao, YW ;

Askenazi, M ;

Halling, C ;

Mullin, L ;

Houmiel, K ;

Gordon, J ;

Vaudin, M ;

Iartchouk, O ;

Epp, A ;

Liu, F ;

Wollam, C ;

Allinger, M ;

Doughty, D ;

Scott, C ;

Lappas, C ;

Markelz, B ;

Flanagan, C ;

Crowell, C ;

Gurson, J ;

Lomo, C ;

Sear, C ;

Strub, G ;

Cielo, C ;

Slater, S .

SCIENCE, 2001, 294 (5550) :2323-2328