Increased expression of N-myc downstream-regulated gene 1 (NDRG1) in placentas from pregnancies complicated by intrauterine growth restriction or preeclampsia

被引：27

作者：

Choi, Suk-Joo ^{[1
]}

Oh, Soo-young

Kim, Jong-Hwa

Sadovsky, Yoel

Roh, Cheong-Rae

机构：

[1] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Obstet & Gynecol, Seoul, South Korea

[2] Washington Univ, Sch Med, Dept Obstet & Gynecol, St Louis, MO 63130 USA

[3] Washington Univ, Sch Med, Dept Cell Biol & Physiol, St Louis, MO 63110 USA

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 2007年 / 196卷 / 01期

基金：

美国国家卫生研究院;

关键词：

intrauterine growth restriction; N-myc downstream-regulated gene; placenta; preeclampsia;

D O I：

10.1016/j.ajog.2006.08.029

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

N-myc downstream-regulated gene 1 is a recently identified gene product that is known to have a role in regulation of trophoblast differentiation and response to injury. By using immuno-staining, Western immunoblotting, and real-time quantitative polymerase chain reaction, we found that the expression of N-myc downstream-regulated gene 1 is upregulated in placentas from pregnancies complicated by intrauterine growth restriction or severe preeclampsia.

引用

页码：45 / 47

页数：3

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