On periodicity and directionality of somitogenesis

被引：24

作者：

Aulehla, Alexander

Pourquie, Olivier

机构：

[1] Howard Hughes Med Inst, Kansas City, MO 64110 USA

[2] Stowers Inst Med Res, Kansas City, MO 64110 USA

来源：

ANATOMY AND EMBRYOLOGY | 2006年 / 211卷 / Suppl 1期

关键词：

embryology; axial patterning; somites; biological models; biological clock;

D O I：

10.1007/s00429-006-0124-y

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

It is currently thought that the mechanism underlying somitogenesis is linked to a molecular oscillator, the segmentation clock, and to gradients of signaling molecules within the paraxial mesoderm. Here, we review the current picture of this segmentation clock and gradients, and use this knowledge to critically ask: What is the basis for periodicity and directionality of somitogenesis?

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页码：S3 / S8

页数：6

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