Modeling the effects of influenza vaccination of health care workers in hospital departments

被引：58

作者：

van den Dool, C. ^{[1
]}

Bonten, M. J. M. ^{[1
,2
]}

Hak, E. ^{[1
,3
]}

Wallinga, J. ^{[1
,4
]}

机构：

[1] UMC Utrecht, Julius Ctr Hlth Sci & Primary Care, NL-3508 GA Utrecht, Netherlands

[2] UMC Utrecht, Dept Med Microbiol, NL-3508 GA Utrecht, Netherlands

[3] Univ Groningen, Univ Med Ctr Groningen, Dept Epidemiol, Groningen, Netherlands

[4] Natl Inst Publ Hlth & Environm, Ctr Infect Dis Control, NL-3720 BA Bilthoven, Netherlands

来源：

VACCINE | 2009年 / 27卷 / 44期

关键词：

Health care worker vaccination; Hospital; Mathematical model; LONG-TERM-CARE; ELDERLY-PEOPLE; MATHEMATICAL-MODEL; TRANSMISSION; INFECTION; TUBERCULOSIS; SENSITIVITY; UNCERTAINTY; MORTALITY; ILLNESS;

D O I：

10.1016/j.vaccine.2009.07.104

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Nowadays health care worker (HCW) vaccination is widely recommended. Although the benefits of this strategy have been demonstrated in long-term care settings, no studies have been performed in regular hospital departments. We adapt a previously developed model of influenza transmission in a long-term care nursing home department to study the effects of HCW vaccination in hospital wards. We study both the effectiveness and efficiency in reducing the hazard rates of influenza virus infection for patients. Most scenarios under study show a similar or higher impact of hospital HCW vaccination than has been predicted for the long-term care nursing home department. Therefore, it seems justified to extend the recommendations for HCW vaccination, based on results in the long-term care setting, to short-term care settings as well. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：6261 / 6267

页数：7

共 31 条

[11] Effectiveness of an influenza vaccine programme for care home staff to prevent death, morbidity, and health service use among residents: cluster randomised controlled trial [J].

Hayward, Andrew C. ;

Harling, Richard ;

Wetten, Sally ;

Johnson, Anne M. ;

Munro, Susan ;

Smedley, Julia ;

Murad, Shahed ;

Watson, John M. .

BRITISH MEDICAL JOURNAL, 2006, 333 (7581) :1241-1244B

[12]

Heesterbeek JAP., 2000, Mathematical Epidemiology of Infectious Diseases: Model Building, Analysis and Interpretation

[13] Effects of antiviral drugs on viral detection in influenza patients and on the sequential infection to their family members-serial examination by rapid diagnosis (Capilia) and virus culture [J].

Hirotsu, N ;

Ikematsu, H ;

Iwaki, N ;

Kawai, N ;

Shigematsu, T ;

Kunishima, O ;

Kashiwagi, S .

OPTIONS FOR THE CONTROL OF INFLUENZA V, 2004, 1263 :105-108

[14] Efficacy and effectiveness of influenza vaccines in elderly people: a systematic review [J].

Jefferson, T ;

Rivetti, D ;

Rivetti, A ;

Rudin, M ;

Di Pietrantonj, C ;

Demicheli, V .

LANCET, 2005, 366 (9492) :1165-1174

[15] Vaccines for preventing influenza in healthy adults (Review) [J].

Jefferson, T. O. ;

Rivetti, D. ;

Pietrantonj, Di C. ;

Rivetti, A. ;

Demicheli, V .

COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2007, (02)

[16] The value of vaccination in chronic kidney disease [J].

Kausz, A ;

Pahari, D .

SEMINARS IN DIALYSIS, 2004, 17 (01) :9-11

[17] Duration of influenza a virus shedding in hospitalized patients and implications for infection control [J].

Leekha, Surbhi ;

Zitterkopf, Nicole L. ;

Espy, Mark J. ;

Smith, Thomas F. ;

Thompson, Rodney L. ;

Sampathkumar, Priya .

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2007, 28 (09) :1071-1076

[18] A COMPARISON OF THREE METHODS FOR SELECTING VALUES OF INPUT VARIABLES IN THE ANALYSIS OF OUTPUT FROM A COMPUTER CODE [J].

MCKAY, MD ;

BECKMAN, RJ ;

CONOVER, WJ .

TECHNOMETRICS, 1979, 21 (02) :239-245

[19] Influenza vaccination levels and influenza-like illness in long-term-care facilities for elderly people in Niigata, Japan, during an influenza A (H3N2) epidemic [J].

Oshitani, H ;

Saito, R ;

Seki, N ;

Tanabe, N ;

Yamazaki, O ;

Hayashi, S ;

Suzuki, H .

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2000, 21 (11) :728-730

[20]

Poole PJ, 2000, COCHRANE DB SYST REV

← 1 2 3 4 →