Factors of the ovarian cancer resistance to combined chemotherapy with platinum preparations

被引：1

作者：

Blyumenberg, AG ^{[1
]}

Gorbacheva, LB ^{[1
]}

Gorbunova, VA ^{[1
]}

Kozachenko, VP ^{[1
]}

Lankin, VZ ^{[1
]}

机构：

[1] RUSSIAN ACAD MED SCI,ONCOL RES CTR,MOSCOW 109801,RUSSIA

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 1996年 / 122卷 / 12期

关键词：

glutathione S-transferase; glutathione peroxidase; glutathione reductase; ovarian cancer; refractority;

D O I：

10.1007/BF02445197

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The glutathione content and the activities of glutathione reductase, glutathione peroxidase, and glutathione S-transferase were measured in biopsy samples of epithelial ovarian cancer. It is shown that in stages 3-4 of ovarian cancer the effectiveness of chemotherapy correlates with the glutathione content and activity of glutathione S-transferase.

引用

页码：1213 / 1216

页数：4