Preparation of nitrogen-containing heterocycles using ring-closing metathesis (RCM) and its application to natural product synthesis

被引：64

作者：

Arisawa, Mitsuhiro

Nishida, Atsushi

Nakagawa, Masako

机构：

[1] Hokkaido Univ, Grad Sch Pharmaceut Sci, Kita Ku, Sapporo, Hokkaido 0600812, Japan

[2] Chiba Univ, Grad Sch Pharmaceut Sci, Inage Ku, Chiba 2638522, Japan

[3] Kanagawa Univ, Dept Chem, Fac Sci, Hiratsuka, Kanagawa 2591293, Japan

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2006年 / 691卷 / 24-25期

关键词：

nitrogen-containing heterocycles; ring-closing metathesis (RCM); chiral bicyclic lactams; azacycloundecenes; axially chiral macrolactams; 1,2-dihydroquinolines; 2-quinolinones; indoles; silyl-enol ether ene metathesis; isomerization of terminal olefins; natural product synthesis;

D O I：

10.1016/j.jorganchem.2006.08.009

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Our synthetic study of nitrogen-containing heterocycles using ring-closing metathesis (RCM), such as chiral bicyclic lactams, azacycloundecenes, axially chiral macrolactams, 1,2-dihydroquinolines, 2-quinolinones and indoles, including a development of silyl-enol ether ene metathesis and isomerization of terminal olefins, are described. Their applications to natural product synthesis are also reported. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：5109 / 5121

页数：13

共 111 条

[41] Macrocycles by ring-closing metathesis [J].