Local radiofrequency-induced hyperthermia using CuNi nanoparticles with therapeutically suitable Curie temperature

被引：53

作者：

Kuznetsov, Anatoly A.

Leontiev, Vladimir G.

Brukvin, Vladimir A.

Vorozhtsov, Georgy N.

Kogan, Boris Ya.

Shlyakhtin, Oleg A.

Yunin, Alexander M.

Tsybin, Oleg I.

Kuznetsov, Oleg A.

机构：

[1] Russian Acad Sci, Inst Biochem Phys, Moscow 119991, Russia

[2] Russian Acad Sci, Inst Met, Moscow 119991, Russia

[3] NIOPIK Organ Intermediates & Dyes Inst, Moscow 103787, Russia

[4] Russian Acad Sci, Inst Chem Phys, Moscow 119991, Russia

来源：

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 2007年 / 311卷 / 01期

关键词：

magnetic fluid hyperthermia; radiofrequency heating; Curie temperature; temperature control by parametric feedback; nanoparticle; copper-nickel alloy; cancer treatment; THERAPY;

D O I：

10.1016/j.jmmm.2006.11.199

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Copper-nickel (CuNi) alloy nanoparticles with Curie temperatures (T-c) from 40 to 60 degrees C were synthesized by several techniques. Varying the synthesis parameters and post-treatment, as well as separations by size and T-c, allow producing mediator nanoparticles for magnetic fluid hyperthermia with parametric feedback temperature control with desired parameters. In vitro and in vivo animal experiments have demonstrated the feasibility of the temperature-controlled heating of the tissue, laden with the particles, by an external alternating magnetic field. (C) 2006 Elsevier B.V. All rights reserved.

引用

页码：197 / 203

页数：7

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