Assessment of vascular wall shear stress and implications for atherosclerotic disease

被引:96
作者
Papaioannou, Theodore G.
Karatzis, Emmanouil N.
Vavuranakis, Manolis
Lekakis, John P.
Stefanadis, Christodoulos
机构
[1] Natl & Kapodistrian Univ Athens, Dept Cardiol 1, Unit Biomed Engn, Sch Med,Hippocration Hosp, Athens 11363, Greece
[2] Natl & Kapodistrian Univ Athens, Attikon Hosp, Sch Med, Dept Cardiol 2, Athens 11363, Greece
关键词
shear stress; atherosclerosis; endothelium; shear rate;
D O I
10.1016/j.ijcard.2006.03.035
中图分类号
R5 [内科学];
学科分类号
1002 [临床医学]; 100201 [内科学];
摘要
Mechanical characteristics of circulation and vasculature, such as blood flow in combination with geometrical features, participate in the generation of several pathophysiological processes, such as development of blood vessel structure, chronic vessel tone regulation, atherosclerosis and others. We aim to briefly describe the basic mechanical and haemodynamic phenomena related to the forces applied to arterial walls, especially shear stresses and the shear-induced physiologic and pathophysiologic processes focusing on those related to atherosclerotic disease. (c) 2006 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:12 / 18
页数:7
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