Options available - from start to finish - for obtaining data from DNA microarrays

被引:159
作者
Holloway, AJ
van Laar, RK
Tothill, RW
Bowtell, DDL
机构
[1] Peter MacCallum Canc Inst, Ian Potter Fdn Ctr Canc Genom & Predict Med, Melbourne, Vic 8006, Australia
[2] Peter MacCallum Canc Inst, Trescowthick Res Labs, Melbourne, Vic 8006, Australia
基金
英国惠康基金;
关键词
D O I
10.1038/ng1030
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Microarray technology has undergone a rapid evolution. With widespread interest in large-scale genomic research, an abundance of equipment and reagents have now become available and affordable to a large cross section of the scientific community. As protocols become more refined, careful investigators are able to obtain good quality microarray data quickly. In most recent times, however, perhaps one of the biggest obstacles researchers face is not the manufacture and use of microarrays at the bench, but storage and analysis of the array data. This review discusses the most recent equipment, reagents and protocols available to the researcher, as well as describing data analysis and storage options available from the evolving field of microarray informatics.
引用
收藏
页码:481 / 489
页数:9
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