Simultaneous occurrence of Hodgkin's lymphoma and eosinophilic granuloma: A potential pitfall in positron emission tomography imaging

被引:20
作者
Naumann, R
Beuthien-Baumann, B
Fischer, R
Kittner, T
Bredow, J
Kropp, J
Ockert, D
Ehninger, G
机构
[1] Dresden Univ Technol, Hosp Carl Gustav Carus, Dept Internal Med 1, Med Klin & Poliklin 1, D-01307 Dresden, Germany
[2] Dresden Univ Technol, Hosp Carl Gustav Carus, Dept Nucl Med, Positron Emiss Tomog Ctr Rossendorf, D-01307 Dresden, Germany
[3] Dresden Univ Technol, Hosp Carl Gustav Carus, Dept Pathol, D-01307 Dresden, Germany
[4] Dresden Univ Technol, Hosp Carl Gustav Carus, Dept Diagnost Radiol, D-01307 Dresden, Germany
[5] Dresden Univ Technol, Hosp Carl Gustav Carus, Dept Surg, D-01307 Dresden, Germany
来源
CLINICAL LYMPHOMA | 2002年 / 3卷 / 02期
关键词
Hodgkin's disease; 2-[F-18]fluorodeoxyglucose; eosinophilic granuloma; Langerhans cell histiocytosis; chemotherapy; mediastinoscopy; radiation therapy;
D O I
10.3816/CLM.2002.n.019
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Positron emission tomography (PET) with [F-18]fluorodeoxyglucose [F-18]FDG has evolved as a method of increasingly clinical importance in the management of patients with malignant lymphoma. However, inflammatory lesions also accumulate [F-18]FDG and may cause difficulties with interpretation. This report deals with 2 patients with simultaneous occurrence of Hodgkin's lymphoma and eosinophilic granuloma, a rare but known coincidence of diseases. In the first case, Hodgkin's disease could not be differentiated from eosinophilic granuloma. Positron emission tomography showed increased [F-18]FDG uptake both in lymphoma manifestations and in the granuloma. In the second case with proven Hodgkin's disease, post-treatment examination showed a positive PET lesion in the mediastinal residual mass, which was interpreted as viable lymphoma. However, histologic examination revealed that it was an eosinophilic granuloma.
引用
收藏
页码:121 / 124
页数:4
相关论文
共 22 条
[21]   Fluorine-18 deoxyglucose and false-positive results: A major problem in the diagnostics of oncological patients [J].
Strauss, LG .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE, 1996, 23 (10) :1409-1415
[22]   Clinical outcomes of pulmonary Langerhans'-cell histiocytosis in adults. [J].
Vassallo, R ;
Ryu, JH ;
Schroeder, DR ;
Decker, PA ;
Limper, AH .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (07) :484-490