A new method of synthesis of fluorescently labelled oligonucleotides and their application in DNA sequencing

被引：35

作者：

Markiewicz, WT ^{[1
]}

Groger, G ^{[1
]}

Rosch, R ^{[1
]}

Zebrowska, A ^{[1
]}

Markiewicz, M ^{[1
]}

Klotz, M ^{[1
]}

Hinz, M ^{[1
]}

Godzina, P ^{[1
]}

Seliger, H ^{[1
]}

机构：

[1] UNIV ULM,SEKT POLYMERE,D-89069 ULM,GERMANY

来源：

NUCLEIC ACIDS RESEARCH | 1997年 / 25卷 / 18期

关键词：

D O I：

10.1093/nar/25.18.3672

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new approach to the chemical synthesis of oligodeoxynucleotides bearing reporter functional groups at base residues of 3'-end nucleosides is reported, Applications of the 3'-end fluorescently labelled primers for automated DNA sequencing are shown.

引用

收藏

页码：3672 / 3680

页数：9

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