No longer an exclusive club: eukaryotic signalling domains in bacteria

被引：91

作者：

Bakal, CJ

Davies, JE

机构：

[1] Princess Margaret Hosp, Ontario Canc Inst, Toronto, ON M5G 2M9, Canada

[2] Univ British Columbia, Dept Microbiol & Immunol, Vancouver, BC V6T 1Z3, Canada

来源：

TRENDS IN CELL BIOLOGY | 2000年 / 10卷 / 01期

关键词：

D O I：

10.1016/S0962-8924(99)01681-5

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Reversible phosphorylation of serine, threonine non tyrosine residues by the interplay of protein kinases and phosphatases plays a key role in regulating many different cellular processes in eukaryotic organisms. A diversity of control mechanisms exists to influence the activity of these enzymes and choreograph the correct concert of protein modifications to achieve distinct biological responses. Such enzymes and their adaptor molecules were long thought to be specific to eukaryotic cellular processes. However, there is increasing evidence that many prokaryotes achieve regulation of key components of cellular function through similar mechanisms.

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页码：32 / 37

页数：10

相关论文

共 41 条

[31] MYXOCOCCUS-XANTHUS, A GRAM-NEGATIVE BACTERIUM, CONTAINS A TRANSMEMBRANE PROTEIN-SERINE THREONINE KINASE THAT BLOCKS THE SECRETION OF BETA-LACTAMASE BY PHOSPHORYLATION [J].

UDO, H ;

MUNOZDORADO, J ;

INOUYE, M ;

INOUYE, S .

GENES & DEVELOPMENT, 1995, 9 (08) :972-983

[32] Expression of the Streptomyces coelicolor A3(2) ptpA gene encoding a phosphotyrosine protein phosphatase leads to overproduction of secondary metabolites in S-lividans [J].

Umeyama, T ;

Tanabe, Y ;

Aigle, BD ;

Horinouchi, S .

FEMS MICROBIOLOGY LETTERS, 1996, 144 (2-3) :177-184

[33] CLONING, SEQUENCING AND EXPRESSION OF SERINE THREONINE KINASE-ENCODING GENES FROM STREPTOMYCES COELICALOR A3(2) [J].

URABE, H ;

OGAWARA, H .

GENE, 1995, 153 (01) :99-104

[34] Cells of Escherichia coli contain a protein-tyrosine kinase, Wzc, and a phosphotyrosine-protein phosphatase, Wzb [J].

Vincent, C ;

Doublet, P ;

Grangeasse, C ;

Vaganay, E ;

Cozzone, AJ ;

Duclos, B .

JOURNAL OF BACTERIOLOGY, 1999, 181 (11) :3472-3477

[35] Characterisation of two putative protein Ser/Thr kinases from actinomycete Streptomyces granaticolor both endowed with different properties [J].

Vomastek, T ;

Nádvorník, R ;

Janecek, J ;

Techniková, Z ;

Weiser, J ;

Branny, P .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1998, 257 (01) :55-61

[36] LIGHT-DEPENDENT TYROSINE PHOSPHORYLATION IN THE CYANOBACTERIUM PROCHLOROTHRIX-HOLLANDICA [J].

WARNER, KM ;

BULLERJAHN, GS .

PLANT PHYSIOLOGY, 1994, 105 (02) :629-633

[37]

WATERS B, 1994, FEMS MICROBIOL LETT, V120, P187

[38] Opposing pairs of serine protein kinases and phosphatases transmit signals of environmental stress to activate a bacterial transcription factor [J].

Yang, XF ;

Kang, CM ;

Brody, MS ;

Price, CW .

GENES & DEVELOPMENT, 1996, 10 (18) :2265-2275

[39] Cloning and characterisation of the pknD gene encoding an eukaryotic-type protein kinase in the cyanobacterium Anabaena sp. PCC7120 [J].

Zhang, CC ;

Libs, L .

MOLECULAR AND GENERAL GENETICS, 1998, 258 (1-2) :26-33

[40] Molecular and genetic analysis of two closely linked genes that encode, respectively, a protein phosphatase 1/2A/2B homolog and a protein kinase homolog in the cyanobacterium Anabaena sp. strain PCC 7120 [J].

Zhang, CC ;

Friry, A ;

Peng, L .

JOURNAL OF BACTERIOLOGY, 1998, 180 (10) :2616-2622

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