Facile enolisation of alpha-ketophosphonates

被引：17

作者：

Afarinkia, K

Echenique, J

Nyburg, SC

机构：

[1] Department of Chemistry, King's College, London WC2R 2LS, The Strand

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 09期

关键词：

D O I：

10.1016/S0040-4039(97)00157-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A number of alpha-ketophosphonate are prepared and shown to he easily enolised. An X-ray crystal structure determination of a beta-phenyl-alpha-ketophosphonate shows the molecule to be present as hydrogen bonded dimers and demonstrates the presence of enol tautomer in solid state. alpha-ketophosphonate can be converted to the corresponding enolacetate under mild conditions. The enolacetate have the E-configuration exclusively. (C) 1997 Elsevier Science Ltd.

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页码：1663 / 1666

页数：4

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