Cell biology - Chromosome territories

被引：276

作者：

Meaburn, Karen J. ^{[1
]}

Misteli, Tom ^{[1
]}

机构：

[1] NCI, NIH, Bethesda, MD 20892 USA

来源：

NATURE | 2007年 / 445卷 / 7126期

关键词：

D O I：

10.1038/445379a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The natural habitat of eukaryotic genomes is the cell nucleus, where each chromosome is confined to a discrete region, referred to as a chromosome territory. This spatial organization is emerging as a crucial aspect of gene regulation and genome stability in health and disease.

引用

页码：379 / 381

页数：3

共 7 条

[1] Chromosome territories, nuclear architecture and gene regulation in mammalian cells
Cremer, T
Cremer, C
[J]. NATURE REVIEWS GENETICS, 2001, 2 (04) : 292 - 301
[2] The genome and the nucleus: a marriage made by evolution - Genome organisation and nuclear architecture
Foster, HA
Bridger, JM
[J]. CHROMOSOMA, 2005, 114 (04) : 212 - 229
[3] Gene order and dynamic domains
Kosak, ST
Groudine, M
[J]. SCIENCE, 2004, 306 (5696) : 644 - 647
[4] Spatial genome organization in the formation of chromosomal translocations
Meaburn, Karen J.
Misteli, Tom
Soutoglou, Evi
[J]. SEMINARS IN CANCER BIOLOGY, 2007, 17 (01) : 80 - 90
[5] Spatial positioning: A new dimension in genome function
Misteli, T
[J]. CELL, 2004, 119 (02) : 153 - 156
[6] Chromosome positioning in the interphase, nucleus
Parada, LA
Misteli, T
[J]. TRENDS IN CELL BIOLOGY, 2002, 12 (09) : 425 - 432
[7] The function of nuclear architecture: A genetic approach
Taddei, A
Hediger, F
Neumann, FR
Gasser, SM
[J]. ANNUAL REVIEW OF GENETICS, 2004, 38 : 305 - 345

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