Combining fluorescent probes and biofunctional magnetic nanoparticles for rapid detection of bacteria in human blood

被引：145

作者：

Gao, Jinhao

Li, Lihua

Ho, Pak-Leung

Mak, Gannon C.

Gu, Hongwei

Xu, Bing

机构：

[1] Hong Kong Univ Sci & Technol, Bioengn Program, Hong Kong, Hong Kong, Peoples R China

[2] Hong Kong Univ Sci & Technol, Dept Chem, Hong Kong, Hong Kong, Peoples R China

[3] Univ Hong Kong, LKS Fac Med, Ctr Infect, Hong Kong, Hong Kong, Peoples R China

[4] Univ Hong Kong, LKS Fac Med, Dept Microbiol, Hong Kong, Hong Kong, Peoples R China

来源：

ADVANCED MATERIALS | 2006年 / 18卷 / 23期

关键词：

D O I：

10.1002/adma.200601058

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Detection of bacteria in human blood within two hours is achieved through the use of vancomycin-functionalized FePt nanoparticles in combination with a vancomycin-conjugated fluorescent probe, as shown in the figure (B: bacteria; Van: vancomycin; FLA: fluorescein amine). This promises to be a sensitive and rapid protocol for detecting bacteria in blood products or other targets in biological samples.

引用

页码：3145 / +

页数：5

共 29 条

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