Obesity in older adults: relationship to functional limitation

被引:102
作者
Jensen, Gordon L. [1 ]
Hsiao, Pao Ying [1 ]
机构
[1] Penn State Univ, Dept Nutr Sci, University Pk, PA 16802 USA
关键词
aging; disability; function; inflammation; obesity; sarcopenia; BODY-MASS INDEX; INDUCED WEIGHT-LOSS; BONE-MINERAL DENSITY; PHYSICAL FUNCTION; KNEE OSTEOARTHRITIS; SARCOPENIC OBESITY; RISK-FACTORS; WAIST CIRCUMFERENCE; MOBILITY LIMITATION; METABOLIC SYNDROME;
D O I
10.1097/MCO.0b013e32833309cf
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of review The present review is intended to provide a critical overview of recent investigations of obesity among older persons with emphasis upon associated functional limitations, potential for intervention, and a future research agenda. Recent findings Obesity is growing in prevalence among older persons. The association between obesity and functional decline is well documented. Recent findings suggest possible contributions of obesity-associated inflammatory milieu, sarcopenia, and impairment of muscle function/strength to adverse functional outcomes. A growing body of literature supports consideration of moderate weight reduction to secure improved metabolic and functional parameters for obese older persons. Summary Obesity is associated with an unfortunate burden of chronic disease, functional limitation, and poor life quality. In view of the growing numbers of afflicted older individuals, there must be research priority to discern how obesity impacts function so that appropriate prevention and treatment strategies may be adopted.
引用
收藏
页码:46 / 51
页数:6
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