Regulators and effectors of the ARF GTPases

被引:325
作者
Donaldson, JG
Jackson, CL
机构
[1] CEA Saclay, Serv Biochim & Genet Mol, F-91191 Gif Sur Yvette, France
[2] NHLBI, Cell Biol Lab, NIH, Bethesda, MD 20892 USA
关键词
D O I
10.1016/S0955-0674(00)00119-8
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The small G proteins of the ARF family are key regulators of membrane dynamics. Many functions of ARF proteins in cells are being revealed by studies of their regulators and effecters. Significant progress has been made over the past year, with the identification of a surprisingly large family of novel ARF GTPase-activating proteins. In addition, two new classes of effecters, the PIP kinases and a novel family of monomeric coat-like proteins have been discovered.
引用
收藏
页码:475 / 482
页数:8
相关论文
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