Mechanisms of disease - The failing heart - An engine out of fuel

被引:1744
作者
Neubauer, Stefan [1 ]
机构
[1] Univ Oxford, John Radcliffe Hosp, Dept Cardiovasc Med, Oxford OX3 9DU, England
关键词
D O I
10.1056/NEJMra063052
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:1140 / 1151
页数:12
相关论文
共 125 条
  • [61] Mitochondrial ATPase and high-energy phosphates in failing hearts
    Liu, JB
    Wang, CS
    Murakami, Y
    Gong, GG
    Ishibashi, Y
    Prody, C
    Ochiai, K
    Bache, RJ
    Godinot, C
    Zhang, JY
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2001, 281 (03): : H1319 - H1326
  • [62] Metabolic modulation - A means to mend a broken heart
    Lopaschuk, GD
    Rebeyka, IM
    Allard, MF
    [J]. CIRCULATION, 2002, 105 (02) : 140 - 142
  • [63] Decreased contractile and metabolic reserve in peroxisome proliferator-activated receptor-α-null hearts can be rescued by increasing glucose transport and utilization
    Luptak, I
    Balschi, JA
    Xing, YQ
    Leone, TC
    Kelly, DP
    Tian, R
    [J]. CIRCULATION, 2005, 112 (15) : 2339 - 2346
  • [64] The PPARγ-activator rosiglitazone does not alter remodeling but increases mortality in rats post-myocardial infarction
    Lygate, CA
    Hulbert, K
    Monfared, M
    Cole, MA
    Clarke, K
    Neubauer, S
    [J]. CARDIOVASCULAR RESEARCH, 2003, 58 (03) : 632 - 637
  • [65] Mechanisms and models in heart failure the biomechanical model and beyond
    Mann, DL
    Bristow, MR
    [J]. CIRCULATION, 2005, 111 (21) : 2837 - 2849
  • [66] MANN DL, 2005, CIRCULATION, V112, pE75
  • [67] Abnormal cardiac and skeletal muscle mitochondrial function in pacing-induced cardiac failure
    Marín-García, J
    Goldenthal, MJ
    Moe, GW
    [J]. CARDIOVASCULAR RESEARCH, 2001, 52 (01) : 103 - 110
  • [68] MALONIC ACIDURIA AND CARDIOMYOPATHY
    MATALON, R
    MICHAELS, K
    KAUL, R
    WHITMAN, V
    RODRIGUEZNOVO, J
    GOODMAN, S
    THORBURN, D
    [J]. JOURNAL OF INHERITED METABOLIC DISEASE, 1993, 16 (03) : 571 - 573
  • [69] Heart failure
    McMurray, JJV
    Pfeffer, MA
    [J]. LANCET, 2005, 365 (9474) : 1877 - 1889
  • [70] Modulation of myocardial energetics - Emerging evidence for a therapeutic target in cardiovascular disease
    Morrow, DA
    Givertz, MM
    [J]. CIRCULATION, 2005, 112 (21) : 3218 - 3221