Synthesis and characterization of a series of lipophilic cisplatin analogs with cis-1,4-diaminocyclohexane as nonleaving amine ligand

A series of lipophilic platinum(II) complexes of the type [Pt(cis-1,4-DACH)L-2] (where cis-1,4-DACH = cis-1,3-diaminocyclohexane and L-acetate, propionate. butyrate, valerate, hexanoate, heptanoate, octanoate, 2,2'-dimethyloctanoate, nonanoate, decanoate, undecanoate, laureate, tridecanoate, myristate, pentadecanoate, palmitate, heptadecanoate, stearate, nonadecanoate, or eicosanoate) has been synthesized and characterized by elemental analysis and by infrared. C-13, and Pt-195 nuclear magnetic resonance spectroscopic techniques.