18F-FDG PET/CT for Image-Guided and Intensity-Modulated Radiotherapy

被引：108

作者：

Ford, Eric C. ^{[1
]}

Herman, Joseph ^{[1
]}

Yorke, Ellen ^{[2
]}

Wahl, Richard L. ^{[3
]}

机构：

[1] Johns Hopkins Univ, Dept Radiat Oncol & Mol Radiat Sci, Baltimore, MD 21231 USA

[2] Mem Sloan Kettering Canc Ctr, Dept Med Phys, New York, NY 10021 USA

[3] Johns Hopkins Univ, Russell H Morgan Dept Radiol & Radiol Sci, Baltimore, MD 21231 USA

来源：

JOURNAL OF NUCLEAR MEDICINE | 2009年 / 50卷 / 10期

关键词：

radiation therapy; IMRT; IGRT; FDG (fluorodeoxyglucose); FDG PET/CT; POSITRON-EMISSION-TOMOGRAPHY; CELL LUNG-CANCER; GROSS TUMOR VOLUME; 4-DIMENSIONAL COMPUTED-TOMOGRAPHY; STEREOTACTIC BODY RADIOTHERAPY; RADIATION-DOSE ESCALATION; BREATH-HOLD PET/CT; FDG-PET; NECK-CANCER; TARGET VOLUMES;

D O I：

10.2967/jnumed.108.055780

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Advances in technology have allowed extremely precise control of radiation dose delivery and localization within a patient. The ability to confidently delineate target tumor boundaries, however, has lagged behind. F-18-FDG PET/CT, with its ability to distinguish metabolically active disease from normal tissue, may provide a partial solution to this problem. Here we review the current applications of F-18-FDG PET/CT in a variety of disease sites, including non-small cell lung cancer, head and neck cancer, and pancreatic adenocarcinoma. This review focuses on the use of F-18-FDG PET/CT to aid in planning radiotherapy and the associated benefits and challenges. We also briefly consider novel radiopharmaceuticals that are beginning to be used in the context of radiotherapy planning.

引用

页码：1655 / 1665

页数：11

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