Aminolysis of Epoxides Using Iridium Trichloride as an Efficient Catalyst

被引：14

作者：

Agarwal, Jyoti ^{[1
]}

Duley, Anju ^{[1
]}

Rani, Rashmi ^{[1
]}

Peddinti, Rama Krishna ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Roorkee 247667, Uttarakhand, India

来源：

SYNTHESIS-STUTTGART | 2009年 / 16期

关键词：

epoxides; iridium trichloride; amines; amino alcohols; aminolysis; AROMATIC-AMINES; ALCOHOLS; CHLORIDE; ANILINES; IRRADIATION; DERIVATIVES; MICROWAVE; CLEAVAGE; TRIFLATE; MILD;

D O I：

10.1055/s-0029-1216899

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Iridium trichloride catalyzes the ring opening of epoxides by aryl, heterocyclic, or aliphatic amines under mild conditions. The reactions proceed at room temperature to afford the corresponding beta-amino alcohols in excellent yields. In general, the aminolysis of cyclopentene oxide is faster than that of cyclohexene oxide in the presence of iridium trichloride as a catalyst.

引用

页码：2790 / 2796

页数：7

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