New microencapsulated sunscreens: technology and comparative evaluation

被引：17

作者：

Anselmi, C

Centini, M

Rossi, C

Ricci, M

Rastrelli, A

Andreassi, M

Buonocore, A

La Rosa, C

机构：

[1] Univ Siena, Dipartimento Farmaco Chim Tecnol, I-53100 Siena, Italy

[2] Univ Siena, Scuola Specializzazione Sci & Tecnol Cosmet, I-53100 Siena, Italy

[3] Univ Perugia, Dipartimento Chim & Tecnol Farmaco, Perugia, Italy

[4] Polytech SC RL, Trieste, Italy

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 2002年 / 242卷 / 1-2期

关键词：

sunscreens; microspheres; substantivity; technology;

D O I：

10.1016/S0378-5173(02)00159-X

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The aim of this work is to obtain new technologically improved microencapsulated sunscreens characterised by UV-radiation stability, good substantivity, low toxicity, a better tolerability and easiness to formulation. For this purpose we prepared two different systems using semisynthetic Hyaluronic Acid (HA) benzyl ester and a synthetic polymer (patent pending). We obtained these systems using two different methodologies: emulsification/solvent evaporation and emulsification/solvent extraction. The comparison between the two formulated systems was carried out in terms of their chemical-physical and biological properties. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：207 / 211

页数：5

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