Oncocytic meningioma

被引:41
作者
Roncaroli, F
Riccioni, L
Cerati, M
Capella, C
Calbucci, F
Trevisan, C
Eusebi, V
机构
[1] OSPED BELLARIA,SEZ ANAT ISTOL & CITOL PATOL MARCELLO MALPIGHI,DIV NEUROSURG,I-40139 BOLOGNA,ITALY
[2] OSPED BELLARIA,DIV NEURORADIOL,I-40139 BOLOGNA,ITALY
[3] UNIV BOLOGNA,DEPT CLIN RADIOL & ANAT PATHOL,SECT ANAT PATHOL MARCELLO MALPIGHI,BOLOGNA,ITALY
[4] UNIV PAVIA,INST PATHOL ANAT,VARESE,ITALY
关键词
meningioma; oncocytoma;
D O I
10.1097/00000478-199704000-00002
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Six cases of meningioma showing oncocytic changes are described. The lesions were composed mostly of sheets, nests, and cords of large polygonal cells with finely granular eosinophilic cytoplasm rich in mitochondria. Neoplastic cells showed nuclear pleomorphism with prominent nucleoli. Necrosis and high mitotic rate were present in the majority of cases. Oncocytic differentiation was demonstrated by conventional histology, immunocytochemistry electron microscopy, and Western-blot analysis. Oncocytic meningiomas showed an aggressive behavior; recurrences were observed in three cases, and invasion of brain cortex was evident in other two cases.
引用
收藏
页码:375 / 382
页数:8
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