Proline-catalysed asymmetric aldol reaction in the room temperature ionic liquid [bmim]PF6

被引：157

作者：

Kotrusz, P ^{[1
]}

Kmentová, I ^{[1
]}

Gotov, B ^{[1
]}

Toma, S ^{[1
]}

Solcániová, E ^{[1
]}

机构：

[1] Comenius Univ, Fac Nat Sci, Dept Organ Chem, Bratislava 84215, Slovakia

来源：

CHEMICAL COMMUNICATIONS | 2002年 / 21期

关键词：

D O I：

10.1039/b206911c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Proline-catalysed asymmetric direct aldol reaction of different aromatic aldehydes with acetone and several other ketones in the room temperature ionic liquid 1-n-butyl-3-methylimidazolium hexafluorophosphate achieved good yields of aldolisation products with reasonable enantioselectivities, even when just 1-5% of proline was used as the catalyst; immobilisation of the catalyst in an ionic liquid phase offers simple product isolation and reuse of the catalytical system in subsequent reactions.

引用

页码：2510 / 2511

页数：2

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