The influence of optical absorption on urinary calculus threshold fluence and ablation efficiency during infrared laser ablation

被引：1

作者：

Chan, KF ^{[1
]}

Hammer, DX ^{[1
]}

Choi, B ^{[1
]}

Vargas, G ^{[1
]}

Sorg, B ^{[1
]}

Pfefer, TJ ^{[1
]}

Teichman, JMH ^{[1
]}

McGuff, HS ^{[1
]}

Pratisto, H ^{[1
]}

Jansen, ED ^{[1
]}

Welch, AJ ^{[1
]}

机构：

[1] Univ Texas, Austin, TX 78712 USA

来源：

BIOMEDICAL APPLICATIONS OF FREE-ELECTRON LASERS | 2000年 / 3925卷

关键词：

ablation efficiency; absorption coefficient; fragmentation efficiency; free electron laser; infrared; kidney stone; optimum wavelength; threshold radiant exposure; tissue ablation;

D O I：

10.1117/12.384253

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The objectives of this study were to determine if the optical absorption properties of urinary calculi affect the threshold fluence for ablation or fragmentation and the ablation efficiency due to laser irradiation. The Vanderbilt free electron laser (FEL) was tuned to selected wavelengths based on the absorption spectrum of various types of urinary calculi. The threshold fluences for ablation of the calculi were measured at different wavelengths. A preliminary study of the ablation efficiency (ablation depth per unit incidence fluence) was performed. The results were found to be in agreement with a thermal ablation model for which the threshold fluences were proportional to 1/mu(a). The ablation efficiencies were higher in regions of the infrared spectra in which absorption was higher. For a fixed laser irradiation, the lower threshold fluences within regions of high optical absorption allowed more energy to enhance calculus ablation. This study provided insight into determining the optimum wavelengths for ablation and laser lithotripsy.

引用

页码：60 / 68

页数：9

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