Drugs, flies, and videotape:: the effects of ethanol and cocaine on Drosophila locomotion

被引：58

作者：

Rothenfluh, A

Heberlein, U

机构：

[1] Univ Calif San Francisco, Dept Anat, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, Program Neurosci, San Francisco, CA 94143 USA

[3] Univ Calif San Francisco, Program Dev Biol, San Francisco, CA 94143 USA

来源：

CURRENT OPINION IN NEUROBIOLOGY | 2002年 / 12卷 / 06期

关键词：

D O I：

10.1016/S0959-4388(02)00380-X

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Drosophila melanogaster has been introduced recently as a model organism in which to study the mechanisms by which drugs of abuse change behavior and by which the nervous system changes upon repeated drug exposure. Surprising similarities between flies and mammals have begun to emerge at the behavioral, neurochemical and molecular levels.

引用

收藏

页码：639 / 645

页数：7

相关论文

共 58 条

[1] Cocaine sensitization and reward are under the influence of circadian genes and rhythm [J].

Abarca, C ;

Albrecht, U ;

Spanagel, R .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (13) :9026-9030

[2] Neurotransmitter transporters as molecular targets for addictive drugs [J].

Amara, SG ;

Sonders, MS .

DRUG AND ALCOHOL DEPENDENCE, 1998, 51 (1-2) :87-96

[3] Circadian modulation of dopamine receptor responsiveness in Drosophila melanogaster [J].

Andretic, R ;

Hirsh, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (04) :1873-1878

[4] Requirement of circadian genes for cocaine sensitization in Drosophila [J].

Andretic, R ;

Chaney, S ;

Hirsh, J .

SCIENCE, 1999, 285 (5430) :1066-1068

[5] Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock [J].

Bae, K ;

Jin, XW ;

Maywood, ES ;

Hastings, MH ;

Reppert, SM ;

Weaver, DR .

NEURON, 2001, 30 (02) :525-536

[6] Dopamine modulates acute responses to cocaine, nicotine and ethanol in Drosophila [J].

Bainton, RJ ;

Tsai, LTY ;

Singh, CM ;

Moore, MS ;

Neckameyer, WS ;

Heberlein, U .

CURRENT BIOLOGY, 2000, 10 (04) :187-194

[7] Addiction, dopamine, and the molecular mechanisms of memory [J].

Berke, JD ;

Hyman, SE .

NEURON, 2000, 25 (03) :515-532

[8] The Drosophila circadian clock:: what we know and what we don't know [J].

Blau, J .

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 2001, 12 (04) :287-293

[9] Trace amines: Identification of a family of mammalian G protein-coupled receptors [J].

Borowsky, B ;

Adham, N ;

Jones, KA ;

Raddatz, R ;

Artymyshyn, R ;

Ogozalek, KL ;

Durkin, MM ;

Lakhlani, PP ;

Bonini, JA ;

Pathirana, S ;

Boyle, N ;

Pu, XS ;

Kouranova, E ;

Lichtblau, H ;

Ochoa, FY ;

Branchek, TA ;

Gerald, C .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (16) :8966-8971

[10] ECTOPIC EXPRESSION IN DROSOPHILA [J].

BRAND, AH ;

MANOUKIAN, AS ;

PERRIMON, N .

METHODS IN CELL BIOLOGY, VOL 44, 1994, 44 :635-654

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