Primary radiation therapy for localized prostate cancer

被引:7
作者
Eng, TY
Thomas, CR
Herman, TS
机构
[1] Univ Texas, Hlth Sci Ctr, Dept Radiat Oncol, San Antonio, TX 78284 USA
[2] Canc Therapy & Res Ctr S Texas, San Antonio, TX 78229 USA
来源
UROLOGIC ONCOLOGY | 2002年 / 7卷 / 06期
关键词
PSA; external beam radiation therapy; brachytherapy; three-dimensional conformal radiotherapy; ultrasound-guided transperineal implant; intensity-modulated radiotherapy; prostate cancer;
D O I
10.1016/S1078-1439(02)00198-9
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Prostate cancer in men is similar to breast cancer in women; both cancers rank first, respectively, in incidence and are normally responsive to radiation therapy. In addition, advances in mammography help detect earlier breast cancers, and the development and refinement of prostatic specific antigen (PSA) has resulted in early detection of low-stage localized prostate cancers. This has generated debate over the proper management of localized prostate cancer. While there have not been any controlled, prospective, randomized trials of sufficient power to compare the various local therapies, based on the current available data, the three commonly used local modalities, surgery, and external beam radiation therapy and brachytherapy (radioactive seed implant), have similar efficacy controlling the disease up to 10 years in many patients. Technological advances in treatment delivery and planning have improved the treatment of prostate cancer with external-beam radiotherapy using three-dimensional conformal radiotherapy (3DCRT), ultrasound-guided transperineal implant, or intensity-modulated radiotherapy (IMRT), as well as proton or neutron beam based therapies. (C) 2002 Elsevier Science Inc. All rights reserved.
引用
收藏
页码:239 / 257
页数:19
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