Covalently bonded adducts of deoxyribonucleic acid (DNA) oligonucleotides with single-wall carbon nanotubes: Synthesis and hybridization

被引:324
作者
Baker, SE [1 ]
Cai, W [1 ]
Lasseter, TL [1 ]
Weidkamp, KP [1 ]
Hamers, RJ [1 ]
机构
[1] Univ Wisconsin, Dept Chem, Madison, WI 53706 USA
关键词
D O I
10.1021/nl025729f
中图分类号
O6 [化学];
学科分类号
0703 [化学];
摘要
We have developed a multistep route to the formation of covalently linked adducts of single-wall carbon nanotubes (SWNT) and cleoxyribonucleic acid (DNA) oligonucleotides. X-ray photoelectron spectroscopy was used to characterize the initial chemical modification to form amine-terminated SWNTs, which were then covalently linked to DNA. The resulting DNA-SWNT adducts hybridize selectively with complementary sequences, with only minimal interaction with noncomplementary sequences.
引用
收藏
页码:1413 / 1417
页数:5
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