Solid phase synthesis of 2-aminobutadienes using a piperazine linker

被引：38

作者：

Hird, NW ^{[1
]}

Irie, K ^{[1
]}

Nagai, K ^{[1
]}

机构：

[1] TAKEDA CHEM IND LTD,YODOGAWA KU,OSAKA 532,JAPAN

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 40期

关键词：

D O I：

10.1016/S0040-4039(97)01633-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of resin-bound 4-substituted-2-aminobutadienes have been synthesised via Wittig reaction with polymer supported 2-(N-piperazino)prop-1-enyl-1-triphenylphosphonium bromide. The use of piperazine provides a readily cleavable enamine linker for attachment of ketones that is compatible with anion chemistry. (C) 1997 Elsevier Science Ltd.

引用

页码：7111 / 7114

页数：4

共 6 条

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