Confocal laser endomicroscopy: technical status and current indications

被引:135
作者
Hoffman, A.
Goetz, M.
Vieth, M.
Galle, P. R.
Neurath, M. F.
Kiesslich, R.
机构
[1] Johannes Gutenberg Univ Mainz, Dept Med 1, D-6500 Mainz, Germany
[2] Bayreuth Hosp, Inst Pathol, Bayreuth, Germany
关键词
D O I
10.1055/s-2006-944813
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Confocal laser endomicroscopy is a newly introduced endoscopic tool that makes it possible to carry out confocal microscopic examination of the mucosal layer during ongoing endoscopy. Different types of tissue and diseases can be diagnosed immediately, facilitating early diagnosis of gastrointestinal cancer. Analysis of the in vivo microarchitecture is helpful in targeting biopsies to relevant areas. In addition, subsurface imaging can unmask microscopic diseases - (microscopic colitis) or bacterial infection (Helicobacter pylori), for example. Molecular imaging is becoming feasible, and this will shortly open the door to new indications in gastrointestinal endoscopy (e.g., in vivo receptor analysis).
引用
收藏
页码:1275 / 1283
页数:9
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